Twin pregnancy obtained with frozen-thawed embryos after in vitro maturation in a patient with polycystic ovarian syndrome

Autor: P-A, Godin, O, Gaspard, F, Thonon, C, Jouan, F, Wijzen, M, Dubois, J-M, Foidart
Rok vydání: 2003
Předmět:
Zdroj: Journal of assisted reproduction and genetics. 20(8)
ISSN: 1058-0468
Popis: A twin pregnancy was obtained in a patient with polycystic ovary syndrome after the transfer of three in vitro maturation-derived day 3 embryos that has been frozen and thawed.The patient had received mild hMG stimulation followed by hCG injection. After culture for 24-48 h, mature oocytes were fertilized by ICSI. Embryos were cultured until day 3; supernumerary embryos were cryopreserved using a slow protocol.Among 15 nonatretic oocytes, 9 matured, 8 were fertilized. Four embryos were transferred but they did not implant. The subsequent transfer of three frozen-thawed embryos resulted in the delivery of two healthy girls.These results indicate that a pregnancy could be obtained with in vitro maturation-derived day-3 frozen-thawed embryos.
Databáze: OpenAIRE