Clevidipine for hypertension treatment in pheochromocytoma surgery

Autor: C, Luis-García, E, Arbonés-Aran, C, Teixell-Aleu, L, Lorente-Poch, L, Trillo-Urrutia
Rok vydání: 2016
Předmět:
Zdroj: Revista espanola de anestesiologia y reanimacion. 65(4)
ISSN: 2341-1929
Popis: Pheochromocytoma is a catecholamine-producing tumour and laparoscopic adrenalectomy is its treatment of choice. During pneumoperitoneum insufflation and tumour handling there is a high risk of massive catecholamine release and hypertensive crisis. After tumour excision, severe arterial hypotension is a common effect, due to relative vasodilation and the residual effect of antihypertensive drugs. We report the case of a patient with pheochromocytoma who was treated with laparoscopic adrenalectomy. During surgical manipulation there was a sudden hypertensive peak that could be controlled quickly with clevidipine infusion. After tumour resection, clevidipine perfusion was stopped and there were no arterial hypotension episodes. Clevidipine is a new intravenous calcium antagonist with rapid onset of action and short half-life that has no residual effect and does not produce arterial hypotension after tumour resection. For these reasons, it can be a first-choice drug for this kind of surgery.
Databáze: OpenAIRE