Virus-induced blast transformation of lymphocytes and its inhibition by F(ab1)2 fragments of human IgG

Autor: Pervikov YuV, G U, Margulis, L B, Elbert, Kulberg AYaU, F S, Baranova
Rok vydání: 1981
Předmět:
Zdroj: Acta virologica. 25(3)
ISSN: 0001-723X
Popis: Blast transformation of lymphocytes from persons immunized by vaccines against tick-borne Japanese encephalitides, in response to stimulation by homologous viral antigens was studied. 3H-Thymidine incorporation into lymphocytes was completely inhibited by F(ab1)2 fragments of normal human IgG containing no antibody to the viruses examined. A correlation of the inhibitory action of F(ab1)2 fragments on lymphocyte transformation induced by viruses and phytohaemagglutinin was observed.
Databáze: OpenAIRE