| Autor: |
E, Tsironi, D, Hadjidakis, E, Mallas, C, Tzathas, D G, Karamanolis, S D, Ladas |
| Rok vydání: |
2008 |
| Předmět: |
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| Zdroj: |
Journal of musculoskeletalneuronal interactions. 8(1) |
| ISSN: |
1108-7161 |
| Popis: |
Most studies have shown contradictory results regarding predictive factors of osteoporosis in inflammatory bowel disease (IBD). Since in these studies either T- or Z-scores has been used, our aim was to compare T- and Z-score in identifying risk factors of osteoporosis in IBD patients.Bone density was measured by dual X-ray absorptiometry (DXA) at L2-L4 of the spine and femoral neck in 122 patients. Twenty-two clinical parameters were recorded prior to DXA and evaluated by univariate and multivariate analysis.On multivariate analysis, cumulative steroid dose was a predictive factor of femoral neck T-score (p0.001) and Z-score (p=0.001). Age was a predictive factor of femoral neck T-score (p0.001). BMI was a predictive factor of femoral neck Z-score (p=0.03). None of the other 19 variables tested had any predictive value for bone density. Ageor=55 years was a risk factor of low femoral neck T-score (OR 5.08, 95% CI 1.90-13.57, p=0.001), as was cumulative dose of prednisoloneor=5 g (OR 3.41, 95% CI 1.50-7.73, p=0.004).There is a discordance of results depending on whether T- or Z-scores are used in analysis. Among 22 parameters, cumulative steroid dose and age proved to be the most important factors. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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