Preparation, Characterization and

Autor: Ana C C, Gouveia, Michele, Munk, Virgínia, Oliveira, Ana P, Ferreira, Humberto M, Brandão, Juliana C, Gern, Roberta, Brayner, Maria A, Martins, Nádia R B, Raposo
Rok vydání: 2020
Předmět:
Zdroj: Journal of nanoscience and nanotechnology. 20(10)
ISSN: 1533-4899
Popis: Cellulose nanofibers have mechanical properties that make them very attractive in a myriad of fields such as biomedicine, tissue engineering, biosensors, cosmetics and food packet products. To evaluate the potential health risks of airborne cellulose nanofibers, the cellulose nanofiber was prepared and characterized and then its pulmonary potential toxicity to a mouse model was studied. Cellulose nanofiber has been prepared by acid hydrolysis of cotton cellulose and characterized by transmission electron microscopy, zeta potential and X-ray diffraction analysis. Then, using a short-term inhalation test, the pulmonary biocompatibility of cotton cellulose nanofibers at different concentrations (0.5 mg/mL, 1 mg/mL and 2 mg/mL) were evaluated. Transmission electron images showed needle-shaped particle with a diameter of about 6-18 nm and a length of 85-225
Databáze: OpenAIRE