| Autor: |
M, Trappolini, S, Matteoli, F M, Chillotti, M, Curione, L R, Del Vecchio, M, Puletti |
| Rok vydání: |
1996 |
| Předmět: |
|
| Zdroj: |
Minerva cardioangiologica. 44(12) |
| ISSN: |
0026-4725 |
| Popis: |
Cigarette smoking is commonly considered as a major risk factor for Acute Myocardial Infarction (AMI). Although AMI has a high incidence in smokers, it doesn't seem to correlate with a worse in hospital prognosis. In order to investigate if cigarette smoking does affect the in-hospital prognosis in patients with AMI, 590 consecutive patients (451 males and 139 females; mean age 63.4 years) admitted to the Coronary Care Unit (CCU) with definite AMI have been studied. Patients were divided in two groups: Group A (303 patients, 269 males and 34 females) smokers till AMI and Group B (287 patients, 182 males and 105 females) nonsmokers or smokers till a month before AMI.The mean age of nonsmokers was higher than smokers (68.4 years vs 58.8 years; p0.001). In addition they showed more frequently hypertension (48.8% vs 38%; p0.001), diabetes (31.3% vs 16.3%; p0.001), and healed infarction or angina (45.6% vs 37.5%). Among Group B higher global mortality rate was observed (22.6% vs 7.6%; p0.001) either among thrombolysed patients (10.1% vs 4.4%; p0.001) either among not thrombolysed (26.9% vs 4.4%; p0.001). The grading in age classes confirmed a higher mortality in nonsmokers patients (6.7% vs 4.9% ageor = 40 andor = 65 years; 32.5% vs 13.3%65 years). They also presented more frequently arrhythmias (15.3% vs 12.2%), ischemic complications (25.4% vs 18.7%), and congestive heart failure (46% vs 34.2%).According to other authors the results of this study confirm a better prognosis in smokers with AMI. Up to authors hypothesis this outcome could be related either to the younger age, a to a different pathogenetic mechanism of coronaric occlusion to raised thrombosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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