Validation of a rapid and economical RP-HPLC method for simultaneous determination of metformin hydrochloride and sitagliptin phosphate monohydrate: Greenness evaluation using AGREE score

Autor: Aqeela, Raza, Syed Hassan, Murtaza, Sana, Hanif, Javed, Iqbal, Ijaz, Ali, Tayyaba, Aftab, Rouheena, Shakir, Rushda, Bedar, Muhammad Ali, Syed
Rok vydání: 2022
Předmět:
Zdroj: Pakistan journal of pharmaceutical sciences. 35(1)
ISSN: 1011-601X
Popis: Reported high performance liquid chromatographic (HPLC) methods for estimating metformin hydrochloride (MET) and sitagliptin phosphate monohydrate (SIT) are either laborious or contain higher proportions of organic solvents in mobile phase, thus presenting exorbitant procedures. So, a rapid, significantly more economical and eco-friendly HPLC method for synchronized analysis of both drugs was aimed to develop and validate in current study. Analytical evaluation was executed on Shimadzou⌖ C
Databáze: OpenAIRE