| Autor: |
K, Kobylińska, J, Pachecka |
| Rok vydání: |
1998 |
| Předmět: |
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| Zdroj: |
Acta poloniae pharmaceutica. 54(6) |
| ISSN: |
0001-6837 |
| Popis: |
The combined effect of carbamazepine (CBZ) and raised environmental temperature on total hepatic cytochrome P450 and on cytochromes P4502B1/2B2 contents was investigated. Carbamazepine produced significant increase of the contents of total cytochrome P450 and cytochromes P4502B1/2B2 in rats exposed to 21 degrees C and 28 degrees C. In contrast exposure of rats of 35 degrees C decreased induction capacity of carbamazepine. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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