| Autor: |
M S, Morozova, V N, Goncharova, T M, Astakhova, T S, Zaĭtseva, I A, Manuilova |
| Rok vydání: |
1994 |
| Předmět: |
|
| Zdroj: |
Akusherstvo i ginekologiia. (1) |
| ISSN: |
0300-9092 |
| Popis: |
Prostaglandins E2 and F2 alpha were measured in decidual tissue of women after spontaneous abortions at pregnancy terms 8 to 10 weeks and after abortions induced by sulprostone, a synthetic prostaglandin E2 analog, at pregnancy term 4-5 weeks. Women in whom pregnancy was terminated surgically at relevant periods were controls. Prostaglandin E2 concentration was found to be 5 times higher and that of prostaglandin F2 alpha 40 times higher in women with spontaneous abortions than in surgical abortion. In sulprostone-induced abortion prostaglandin concentrations in decidual tissue were the same as in controls. These data indicate that a drastic increase of prostaglandin levels in spontaneous abortion is not only a result of myometrial contractions or decidual tissue rejection, but an important component in the chain of events leading to miscarriage. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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