Mismatch repair, somatic mutations, and the origins of cancer

Autor:	D G, MacPhee
Rok vydání:	1995
Předmět:	DNA Replication DNA Bacterial Phenotype Time Factors DNA Repair Neoplasms Mutation Escherichia coli Humans Interphase Cell Division
Zdroj:	Cancer research. 55(23)
ISSN:	0008-5472
Popis:	This paper outlines the basic properties of a newly recognized pathway that should enable somatic cells to generate double-stranded mutations in the complete absence of cell proliferation. Recognition of the existence of this pathway provides us with the basis for a better understanding of a number of important biological phenomena and, in particular, may help us to understand the origins of cancers in unselected human populations.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1149db8388e7d211eaa2744d70077cce https://pubmed.ncbi.nlm.nih.gov/7585619 Zobrazit plný text záznamu