| Autor: |
Hui, Liang, Dong-Sheng, Ji, Guo-Qiang, Xu, Yong-Chun, Luo, Haixue, Zheng, Peng-Fei, Xu |
| Rok vydání: |
2021 |
| Zdroj: |
Chemical science. 13(4) |
| ISSN: |
2041-6520 |
| Popis: |
Using diverse carbon-centered radical precursors and electron-rich (hetero)aromatics and alcohols as nucleophiles, a visible-light driven chiral phosphoric acid (CPA) catalyzed asymmetric intermolecular, three-component radical-initiated dicarbofunctionalization and oxytrifluoromethylation of enamines was developed, which provides a straightforward access to chiral arylmethylamines, aza-hemiacetals and γ-amino acid derivatives with excellent enantioselectivity. As far as we know, this is the first example of constructing a chiral C-O bond using simple alcohols |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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