| Autor: |
W S, Wan Ab Rahman, W Z, Abdullah, M N, Hassan, S, Ahmed, Z, Zulkafli, W A, Wan Ahmed, S, Iberahim, N H, Mohd Noor |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
The Malaysian journal of pathology. 43(3) |
| ISSN: |
0126-8635 |
| Popis: |
Plasma protein-C is a natural anticoagulant that inactivates factors Va and VIIIa. Familial protein C deficiency is inherited as an autosomal dominant disorder. The homozygous or compound heterozygous type may present early as purpura fulminant, while the heterozygous type can present as thromboembolism later in life. Presented in this report is a case of a 21-year-old female patient with protein-C deficiency, confirmed by thrombophilia investigations. She experienced recurrent deep vein thrombosis and cerebral sinus thrombosis due to thrombotic occlusion. She had a family history of deep vein thrombosis. Hence, high-risk cases should be seriously considered for long term anticoagulation therapy. The utility versus futility of thrombophilia testing in a particular situation is discussed to address and ensure safe practice among patients with thromboembolism. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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