Autor: |
Iu V, Egorov, V I, Stolbova, V S, Kuz'min, L V, Rozenshtraukh |
Rok vydání: |
2012 |
Předmět: |
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Zdroj: |
Kardiologiia. 52(2) |
ISSN: |
0022-9040 |
Popis: |
Myocardial cells in pulmonary veins are thought to play a major role in the initiation and maintenance of atrial arrhythmias, including atrial fibrillation. In experiments on rat pulmonary veins, antiarrhythmic drug niferidil (RG-2) produced increase of APD90% and functional refractory period and decrease of action potential amplitude and slope of APD restitution curve. Thus niferidil (RG-2) exerts stronger action on pulmonary veins than left atrium. This can take important part in Niferidil (RG-2) antiarrhythmic activity. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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