[Pharmacological correction by roxicam of the prostacyclin-thromboxane system in acute myocardial infarction complicated by heart failure]

Autor:	O I, Shushliapin, A N, Shelest, A F, Khosseĭn Shakhavat
Rok vydání:	1991
Předmět:	Heart Failure Nitrates Aspirin Anti-Inflammatory Agents Non-Steroidal Myocardial Infarction Thromboxanes 6-Ketoprostaglandin F1 alpha Epoprostenol Cardiac Glycosides Thromboxane B2 Piroxicam Thromboxane A2 Humans Diuretics
Zdroj:	Kardiologiia. 31(8)
ISSN:	0022-9040
Popis:	The prostaglandin-thromboxane system, platelet hemostasis and central hemodynamics were evaluated in 51 patients with heart failure-complicated acute myocardial infarction during aspirin, roxicam and basic (nitrates + cardiac glycosides + diuretics) therapies. The new non-steroidal antiinflammatory agent roxicam was shown to selectively inhibit thromboxane, without affecting prostacyclin levels. The agent may be regarded as the drug of choice in using antiaggregatory therapy in patients with myocardial infarction concurrent with heart failure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1049acce3f50c47af6b03bc7c1167961 https://pubmed.ncbi.nlm.nih.gov/1795470 Zobrazit plný text záznamu