[Efficacy of a daily application of mesalazine (Pentasa) suppository with progressive release, in the treatment of ulcerative proctitis. A double-blind versus placebo randomized trial]

Autor: Y, Ngô, J M, Gélinet, A, Ivanovic, J, Kac, G, Schénowitz, J, Vilotte, J C, Rambaud
Jazyk: francouzština
Rok vydání: 1992
Předmět:
Zdroj: Gastroenterologie clinique et biologique. 16(10)
ISSN: 0399-8320
Popis: Therapeutic efficacy of mesalazine controlled-release suppository 1 g once daily was compared with that of a placebo during 2 weeks in 50 patients (26 in the mesalazine group, 24 in the placebo group) with ulcerative proctitis, in a double-blind randomized trial. Endoscopic and clinical remission was seen in 69 and 65% of mesalazine-treated patients and in 33 and 25% of placebo-treated patients respectively (Por = 0.01). No side effects were seen. It is concluded that a once-a-day administration of 1 g mesalazine controlled-release suppository is effective for topical treatment of patients with ulcerative proctitis.
Databáze: OpenAIRE