Randomised double blind placebo controlled clinical trial of sucralfate and ranitidine in chronic duodenal ulcer

Autor: K V, Nair, T M, Ramachandran, V, Thomas, T, Rajindranath
Rok vydání: 1990
Předmět:
Zdroj: The Journal of the Association of Physicians of India. 38(3)
ISSN: 0004-5772
Popis: A double blind, randomised, placebo controlled clinical trial was carried out in endoscopically proved chronic duodenal ulcer patients to compare the efficacy of sucralfate and ranitidine. Sucralfate 1 g four times daily and ranitidine 150 mg twice daily were found to be equally effective in inducing ulcer healing (73.1% and 82.1% respectively) during the 6-week treatment period. The rate of recurrence of the ulcer within six months after the initial treatment (84.2% and 82.6%) was also comparable in the sucralfate and ranitidine groups. Sucralfate and ranitidine are equally effective in ulcer healing and prevention of ulcer relapse.
Databáze: OpenAIRE