| Autor: |
Unmesh, Mohite, Anil, Pathare, Salam, al Kindi, Devendra, Hiwase, Nirmala, Vadakkepat, Huxley, Knox-Macaulay |
| Rok vydání: |
2003 |
| Předmět: |
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| Zdroj: |
Haematologia. 32(4) |
| ISSN: |
0017-6559 |
| Popis: |
We report an unusual case of a 40-year-old female patient with a severe case of direct Coombs positive haemolytic anaemia, moderate hepatomegaly and marked splenomegaly. Her initial response to steroids was transient and was rapidly followed by a relapse. Therefore, she underwent splenectomy both as a therapeutic measure and to rule out an underlying lymphoproliferative disorder. Histopathological examination of the excised spleen, as well a liver biopsy, revealed extensive extramedullary haematopoiesis, while significant marrow fibrosis was noted in a trephine biopsy sample. These findings confirmed the concomitant diagnosis of agnogenic myeloid metaplasia with myelofibrosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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