| Autor: |
Li, Luo, Yanping, Hu, Fengge, Liu, Jianjie, Yang, Yang, Bai, Yutong, Meng, Ran, Ding, Mingzhu, Hu, Linguo, Wu |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Annals of clinical and laboratory science. 52(5) |
| ISSN: |
1550-8080 |
| Popis: |
The World Health Organization in its 2019 Classification of Breast Tumors termed breast sebaceous carcinoma as invasive breast carcinoma of no special type (IBC-NST), with a sebaceous pattern. Approximately 30 cases of IBC-NST with a sebaceous pattern have been reported in the literature, and in all cases the expression of mismatch repair proteins in tumors was normal. Here, we report a case of IBC-NST with a sebaceous pattern and high-frequency microsatellite instability (MSI-H). This case was a sporadic sebaceous pattern of IBC-NST with MSI-H and was unrelated to Muir-Torre syndrome. Its histopathological characteristics were similar to those of MSI-H-associated triple-negative breast carcinoma (TNBC) with a high histological grade but were without tumor-infiltrating lymphocytes (TILs). The tumor did not recur after 20 months of follow-up. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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