| Autor: |
A A, Eremenko, T P, Ziuliaeva, L V, Bozh'eva, R Iu, Borisov |
| Rok vydání: |
1999 |
| Předmět: |
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| Zdroj: |
Anesteziologiia i reanimatologiia. (5) |
| ISSN: |
0201-7563 |
| Popis: |
Comparison of the hypotensive effects of lomir (isradipine) and adalat (nifedipine) in 36 patients showed lomir to be more effective after aortocoronary bypass surgery. Normalization of arterial pressure started 5-10 min after lomir infusion, followed by a 24.5% increase in cardiac output and decrease in peripheral vascular resistance by 43.8%. Arterial pressure did not rise after lomir infusion was discontinued. With adalat, arterial pressure normalized 30 min later, and the therapeutic effect was achieved with a very high dose (5-7 times higher than recommended). Cardiac output did not change, and cardiac arrhythmias were observed in 11.7% patients. Therefore, lomir is a preferable Ca channel blocker for treating postoperative arterial hypertension after aortocoronary bypass surgery. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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