Respiratory impedance in patients with Duchenne muscular dystrophy

Autor: Laura, Gochicoa-Rangel, Mario H, Vargas, José Luis, Alonso-Gómez, Luis, Rodríguez-Moreno, David, Martínez-Briseño, Omar, Baños-Mejía, Luis, Torre-Bouscoulet
Rok vydání: 2014
Předmět:
Zdroj: Pediatric pulmonology. 51(10)
ISSN: 1099-0496
Popis: Impulse oscillometry (IOS) evaluates non-effort-dependent respiratory mechanics, and thus it may be useful to evaluate patients with Duchenne muscular dystrophy (DMD).We aimed (1) to describe the behavior of IOS parameters in patients with DMD, and compare it to those from a control group; (2) to determine whether resistances and reactances differ in relation to the severity of DMD; and (3) to compare IOS parameters with spirometry and maximal inspiratory (MIP) and expiratory (MEP) pressures.Children and adolescents (20 years old) with biopsy-confirmed DMD and age-paired subjects were cross-sectionally evaluated. All results were transformed to z scores with respect to the healthy subjects (reference population).Anthropometric characteristics did not differ between the 31 patients and 69 controls included in the study. Compared with controls, patients with DMD had higher IOS resistances and lower reactances. As expected, FEVThis study showed that IOS is feasible in children and adolescents with DMD and yields information about respiratory function not achievable with the usual forced techniques. Pediatr Pulmonol. 2016;51:1072-1079. © 2016 Wiley Periodicals, Inc.
Databáze: OpenAIRE