pH-Responsive Transferrin-pHlexi Particles Capable of Targeting Cells

Autor: Adelene S M, Wong, Ewa, Czuba, Moore Z, Chen, Daniel, Yuen, Kristofer I, Cupic, Shenglin, Yang, Rebecca Y, Hodgetts, Laura I, Selby, Angus P R, Johnston, Georgina K, Such
Rok vydání: 2022
Zdroj: ACS macro letters. 6(3)
ISSN: 2161-1653
Popis: Targeting nanoparticles to specific cellular receptors has the potential to deliver therapeutic compounds to target sites while minimizing side effects. To this end, we have conjugated a targeting protein, holo-transferrin (holo-Tf), to pH-responsive polymers, poly(2-(diethylamino)ethyl methacrylate) (PDEAEMA) and poly(2-(diethylamino)ethyl methacrylate)
Databáze: OpenAIRE