Norovirus strains in patients with acute gastroenteritis in rural and low-income urban areas in northern Brazil

Autor:	Rory J, Tinker, Antonio Charlys, da Costa, Roozbeh, Tahmasebi, Flavio Augusto de Pádua, Milagres, Vanessa, Dos Santos Morais, Ramendra Pati, Pandey, Alexis, José-Abrego, Rafael, Brustulin, Maria da Aparecida, Rodrigues Teles, Mariana Sequetin, Cunha, Emerson Luiz Lima, Araújo, Mariela Martínez, Gómez, Xutao, Deng, Eric, Delwart, Ester Cerdeira, Sabino, Elcio, Leal, Adriana, Luchs
Rok vydání:	2020
Předmět:	Molecular Epidemiology Base Sequence Genotype Norovirus Genetic Variation High-Throughput Nucleotide Sequencing Gastroenteritis Feces Cross-Sectional Studies Humans RNA Viral Poverty Brazil Phylogeny Caliciviridae Infections
Zdroj:	Archives of virology. 166(3)
ISSN:	1432-8798
Popis:	From 2010-2016, a total of 251 stool samples were screened for norovirus using next-generation sequencing (NGS) followed by phylogenetic analysis to investigate the genotypic diversity of noroviruses in rural and low-income urban areas in northern Brazil. Norovirus infection was detected in 19.9% (50/251) of the samples. Eight different genotypes were identified: GII.4_Sydney[P31] (64%, 32/50), GII.6[P7] (14%, 7/50), GII.17[P17] (6%, 3/50), GII.1[P33] (6%, 3/50), GII.3[P16] (4%, 2/50), GII.2[P16] (2%, 1/50), GII.2[P2] (2%, 1/50), and GII.4_New Orleans[P4] (2%, 1/50). Distinct GII.6[P7] variants were recognized, indicating the presence of different co-circulating strains. Elucidating norovirus genetic diversity will improve our understanding of their potential health burden, in particular for the GII.4_Sydney[P31] variant.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::0c0e82e408d124a9d38d46edf965eb9a https://pubmed.ncbi.nlm.nih.gov/33462673 Zobrazit plný text záznamu Full text from SpringerLink