Autor: |
J, Bonneterre, J M, Pion, A, Demaille |
Jazyk: |
francouzština |
Rok vydání: |
1987 |
Předmět: |
|
Zdroj: |
Bulletin du cancer. 74(3) |
ISSN: |
0007-4551 |
Popis: |
One hundred-twenty-seven advanced breast cancer patients who had been -for most of them- heavily pretreated with chemo- and/or hormone therapy received 500 mg aminoglutethimide and 30 mg hydrocortisone/day. The response rate was 20% (58% when stabilizations were included); the best responses were observed in skin and node metastases. The response rate in bone metastasis was 16%. The general condition of the patient (according to the Karnofsky index) was improved in 50% of the responders (including stabilizations) and in 23% of the non-responders. The survival of patients who were only stabilized was close to the survival of responders. The tolerability of this treatment was very good. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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