Targeted Elimination of

Autor: Peisi, Li, Peng, Wan, Ruonan, Zhao, Jin, Chen, Xiaoshen, Li, Jie, Li, Wenguang, Xiong, Zhenling, Zeng
Rok vydání: 2022
Zdroj: Infection and drug resistance. 15
ISSN: 1178-6973
Popis: Plasmid-borne carbapenem resistance geneA series of CRISPR-Cas9 plasmids was constructed, and specific guide RNAs(sgRNA) were designed to target theThe results showed that pCas9, pCas9-oriT and pBAD-Cas9-oriT can effectively eliminateThe CRISPR-Cas9 system achieved plasmid clearance and simultaneous re-sensitization to meropenem in
Databáze: OpenAIRE