A multicentric study with arteether in patients of uncomplicated falciparum malaria

Autor: O P, Asthana, J S, Srivastava, V P, Kamboj, N, Valecha, V P, Sharma, S, Gupta, T K, Pande, K A, Vishwanathan, K M, Mahapatra, N C, Nayak, P K, Mahapatra, J, Mahanta, V K, Srivastava, Vasdev, N, Singh, M M, Shukla, A B, Balsara, S K, Mishra, S K, Satpathy, S, Mohanty, B, Dash
Rok vydání: 2001
Předmět:
Zdroj: The Journal of the Association of Physicians of India. 49
ISSN: 0004-5772
Popis: Two hundred and sixty seven patients of uncomplicated P. falciparum malaria completed study in a multicentric phase III clinical trial of Arteether. Arteether was given intramuscularly in a dose of 150 mg daily for three consecutive days. Each patient was followed upto 28 days of alpha, beta arteether therapy. The cure rate was 97% with fever clearance time between 1-7 days (24-168 hours) and parasite clearance time between 1-3 days (24-72 hours). Parasite reappearance rate was found to be 3% and reported at only three of the centres. Following the treatment no adverse effect was observed on haematological, biochemical and vital clinical parameters.
Databáze: OpenAIRE