Regulation of the tubulin polymerization-promoting protein by Ca

Autor: Seita, Doi, Naoki, Fujioka, Satomi, Ohtsuka, Rina, Kondo, Maho, Yamamoto, Miwako, Denda, Masaki, Magari, Naoki, Kanayama, Naoya, Hatano, Ryo, Morishita, Takafumi, Hasegawa, Hiroshi, Tokumitsu
Rok vydání: 2021
Předmět:
Zdroj: Cell calcium. 96
ISSN: 1532-1991
Popis: To elucidate S100 protein-mediated signaling pathways, we attempted to identify novel binding partners for S100A2 by screening protein arrays carrying 19,676 recombinant glutathione S-transferase (GST)-fused human proteins with biotinylated S100A2. Among newly discovered putative S100A2 interactants, including TMLHE, TRH, RPL36, MRPS34, CDR2L, OIP5, and MED29, we identified and characterized the tubulin polymerization-promoting protein (TPPP) as a novel S100A2-binding protein. We confirmed the interaction of TPPP with Ca
Databáze: OpenAIRE