Antimetastatic action of diltiazem on LS/BL tumor cells in liver tumor-colony assay

Autor:	V, Jurásková, T, Sládek
Rok vydání:	1990
Předmět:	Male Dose-Response Relationship Drug Lymphoma Non-Hodgkin Liver Neoplasms Drug Evaluation Preclinical Antineoplastic Agents Mice Inbred Strains Neoplastic Cells Circulating Cell Line Lethal Dose 50 Diltiazem Mice Animals Female Neoplasm Metastasis
Zdroj:	Neoplasma. 37(3)
ISSN:	0028-2685
Popis:	Inhibition of experimental metastases of lymphosarcoma LS/BL cells by diltiazem, a calcium blocking agent, was tested. Diltiazem treatment (2 X 30 mg/kg p.o. for 12 days) resulted in a maximum of 72.8% inhibition of liver metastases. The authors suggest that diltiazem might become suitable candidate for antimetastatic treatment in humans.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::0b6b32a086caa74e6a11b6d8e26d9a8b https://pubmed.ncbi.nlm.nih.gov/2370918 Zobrazit plný text záznamu