Response of murine DNA polymerases C and N to partial hepatectomy

Autor:	M J, Plummer, M J, Evans
Rok vydání:	1976
Předmět:	Mice Inbred C57BL Chromatography Mice Liver DNA Nucleotidyltransferases Chromatography Gel Animals Hepatectomy Female Cell Division
Zdroj:	Journal of medicine. 7(1)
ISSN:	0025-7850
Popis:	Two DNA polymerases, designated C and N have been characterized in extracts of murine spleen and liver (Evans et al. 1974). The effect of partial hepatectomy on the activity levels of these two enzymes was studied by gel filtration of crude extracts on Sephadex G-200. Both enzymes were observed to respond to the proliferation stimulus. Polymerase N activity reached maximum levels between 30 and 48 hours after hepatectomy. Polymerase C response was delayed until 30 hours and reached maximum values at 48-72 hours.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::0b5fb8f5d42bcb614c61920e56083567 https://pubmed.ncbi.nlm.nih.gov/1064680 Zobrazit plný text záznamu