Prognostic value of hemoglobin levels prior to radiotherapy for cervical cancer--Kuwait experience

Autor: S, Abuzallouf, S, Vasishta, A, Ragheb, A, Varghese, O, El-Hattab
Rok vydání: 2010
Předmět:
Zdroj: The Gulf journal of oncology. (3)
ISSN: 2078-2101
Popis: To evaluate hemoglobin (Hb) levels before and during radiotherapy and its role as prognostic factor on treatment results of patients treated for cancer cervix.One hundred and seven patients with cervical cancer were registered and managed at KCCC during 1995 - 1999. The pre-treatment and mid treatment Hb levels were found for 47 patients only. Follow-up was done for these cases aiming at evaluation the overall and disease-free survival. Statistical analysis was done using SPSS statistical package version 10.0.The median age of patients were 45 and ranged between 26-80 years. Kuwaiti patients represented 21.3% of cases. The most common stage was Stage IIb representing 51.1% followed by IIIb representing 27.7%. Stage Ib and IIa represented 12.8%. About 89.4% were squamous cell carcinoma, while adenocarcinoma was 6.4%. Treatment outcome revealed 18 relapses (38.3%). Disease-free survival for cases with pre-treatment Hb level12 was 16.3%, while for those with Hb levelor = 12 g/dL it was 62.9%. The difference was statistically significant (P = 0.02).Patients with pre-treatment Hb12 g/dL had a significantly lower disease-free survival.
Databáze: OpenAIRE