| Autor: |
L, Cellini, L, Marzio, A, Di Girolamo, N, Allocati, L, Grossi, B, Dainelli |
| Rok vydání: |
1991 |
| Předmět: |
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| Zdroj: |
FEMS microbiology letters. 68(3) |
| ISSN: |
0378-1097 |
| Popis: |
The in vitro antibacterial activity of omeprazole against eight strains of Helicobacter pylori was evaluated. Minimum inhibitory concentration (MIC) values were 32 micrograms/ml and 64 micrograms/ml (MIC50 and MIC90 respectively). We performed a randomized single blind study comparing the efficacy of omeprazole alone (for 4 weeks) or combined with roxithromycin (for 2 weeks) in the treatment of duodenal ulcer and chronic active gastritis associated with H. pylori infection, H. pylori was eradicated in 75% of patients treated with omeprazole alone whereas the patients treated with the combination of these drugs were completely free from H. pylori at the end of the therapy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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