[Bacteriological substantiation of the antituberculosis effect of immunotropic drug tubosan]

Autor:	B S, Kibrik, A V, Pavlov, O G, Chelnokova
Rok vydání:	2013
Předmět:	Microbial Viability Antitubercular Agents Microbial Sensitivity Tests Mycobacterium tuberculosis Russia Hydrazines Pyrimidines Treatment Outcome Adjuvants Immunologic Case-Control Studies Tuberculosis Multidrug-Resistant Humans Sulfones Tuberculosis Pulmonary
Zdroj:	Eksperimental'naia i klinicheskaia farmakologiia. 76(2)
ISSN:	0869-2092
Popis:	The antituberculosis effect of tubosan registered in the Russian Federation as an immunostimulant drug has been studied on a series of 53 clinical strains of Mycobacterium tuberculosis (MBT). It is established that tubosan produces a bactericidal effect on drug-sensitive MBT strains and a bacteriostatic effect on resistant MBT strains. Use of tubosan for the treatment of 102 patients with drug-resistant destructive tuberculosis showed evident clinical-radiological involution process, with prospects of clinical recovery for 75% of patients. Results of this study show that tubosan possesses both antituberculosis and immunostimulant properties. It is recommended to use tubosan for complex treatment of patients with drug-resistant tuberculosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::0a86440b502020f52c71aa7b599a1a05 https://pubmed.ncbi.nlm.nih.gov/23631279 Zobrazit plný text záznamu