[Local and systemic bone effects of rheumatoid arthritis]

Autor:	M, Rauner, L C, Hofbauer, M, Aringer
Jazyk:	němčina
Rok vydání:	2012
Předmět:	Arthritis Rheumatoid Treatment Outcome Bone Density Conservation Agents Humans Osteoporosis Calcium Vitamin D Glucocorticoids Immunosuppressive Agents
Zdroj:	Zeitschrift fur Rheumatologie. 71(10)
ISSN:	1435-1250
Popis:	Rheumatoid arthritis (RA) is a bone-destructive disease that is a serious risk factor for the development of osteoporosis, which is defined by a loss in bone quality and an increased fracture risk. The proinflammatory cytokines tumor necrosis factor-α (TNFα), interleukin-6 (IL-6) and IL-17, in particular, contribute to local and systemic bone loss in RA. While effectively reducing inflammation, glucocorticoids add to the fracture risk. Therefore, an adequate supply of calcium and vitamin D is essential. For many patients with RA, bone density measurements are recommended.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::0a7d2684aee41fa4c49084d35cf7d1f0 https://pubmed.ncbi.nlm.nih.gov/22806699 Zobrazit plný text záznamu Full text from SpringerLink