Two-year analysis of changes in the optic nerve and retina following anti-VEGF treatments in diabetic macular edema patients

Autor: Richard, Filek, Phil, Hooper, Tom G, Sheidow, John, Gonder, Subrata, Chakrabarti, Cindy Ml, Hutnik
Rok vydání: 2018
Předmět:
Zdroj: Clinical Ophthalmology (Auckland, N.Z.)
ISSN: 1177-5467
Popis: Purpose: To evaluate long-term structural and functional changes that happen to the optic nerve and retina following ranibizumab (Lucentis) injections in diabetic macular edema (DME) patients. Methods: Patients with clinically significant DME requiring anti-VEGF injections underwent pre-injection baseline, 6, 12, and 24 month follow-up tests. The tests performed were optical coherence tomography (OCT), best-corrected visual acuity (BCVA), and visual field (VF). Wide-field fluorescein angiogram (IVFA) was performed to monitor the progression of diabetic ischemia. Results: A total of 30 patients requiring anti-VEGF injections and 21 control patients not requiring anti-VEGF injections were enrolled in the study. From baseline, the average macular thickness significantly decreased (p
Databáze: OpenAIRE