Protease inhibitors activity in lepromatous leprosy and lepra reaction

Autor:	V L, Yemul, S R, Sengupta, T N, Dhole
Rok vydání:	1983
Předmět:	Adult Male Erythema Nodosum Adolescent Leprosy alpha 1-Antitrypsin Humans Female Middle Aged Child
Zdroj:	Leprosy in India. 55(1)
ISSN:	0024-1024
Popis:	Serum alpha one antitrypsin levels were measured in 50 healthy age and sex matched controls with 45 lepromatous leprosy cases and 5 cases of lepra reaction. It was noted that the mean level in healthy controls was 281.00 mg%, while the mean levels in LL patients was 421.00 mg% and in LR 570.00 mg%. The elevation of Alpha one antitrypsin was statistically significant in LL patients. It is possible that the rise is a reaction to release of proteases and or higher complement activity, which are the results of a high bacillary loading to formation of immune complexes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::0a5902d32c08fffe9df3ccd40b675c00 https://pubmed.ncbi.nlm.nih.gov/6603564 Zobrazit plný text záznamu