[The preclinical assessment of the activity and pharmacological action of native human interleukin-2]

Autor: N V, Malakhova, I D, Treshchalin, M S, Iobadze, I F, Abronina, S N, Bykovskaia, S F, Iushkov, E R, Pereverzeva, A B, Syrkin, M O, Raushenbakh
Rok vydání: 1990
Předmět:
Zdroj: Patologicheskaia fiziologiia i eksperimental'naia terapiia. (2)
ISSN: 0031-2991
Popis: It was demonstrated in in vivo and in vitro experiments that interleukin-2, obtained by cultivation of donor lymphocytes and purified by gel filtration, induces the production of mouse and human killer lymphocytes possessing high cytolytic activity against tumor cells. Interleukin-2 does not cause irreversible changes of the physiological and morphologic indices of vital activity in mice.
Databáze: OpenAIRE