Conformational properties of N',N'-dimethylamides of N-acetyldehydroalanine and N-acetyl-(Z)-dehydrophenylalanine

Autor: D, Siodłak, M A, Broda, B, Rzeszotarska, A E, Kozioł, I, Dybała
Rok vydání: 2002
Předmět:
Zdroj: Acta biochimica Polonica. 48(4)
ISSN: 0001-527X
Popis: Conformational preferences of Ac-deltaAla-NMe2 and Ac-(Z)-deltaPhe-NMe2 were studied and compared with those of their monomethyl counterparts as well as with those of their saturated analogues. X-Ray data and energy calculations revealed a highly conservative conformation of the dehydro dimethylamides, which is located in a high-energy region of the Ramachandran map.
Databáze: OpenAIRE