A B cell-specific differentiation antigen, CD23, is a receptor for IgE (Fc epsilon R) on lymphocytes

Autor:	K, Yukawa, H, Kikutani, H, Owaki, K, Yamasaki, A, Yokota, H, Nakamura, E L, Barsumian, R R, Hardy, M, Suemura, T, Kishimoto
Rok vydání:	1987
Předmět:	B-Lymphocytes Receptors IgE Antibodies Monoclonal Cell Differentiation DNA Receptors Fc Immunoglobulin E Antigens Differentiation B-Lymphocyte Mice L Cells Transformation Genetic Antigens Surface Animals Humans Receptors Immunologic
Zdroj:	Journal of immunology (Baltimore, Md. : 1950). 138(8)
ISSN:	0022-1767
Popis:	Two independent L cell transformants expressing human lymphocyte Fc epsilon R were established by using cellular DNA from RPMI 8866 cells. The surface expression of the receptor was confirmed on the basis of the binding of a panel of anti-Fc epsilon R antibodies and its ability to bind IgE. Anti-CD23 antibodies strongly stained the transformants, indicating possible identity or antigenic relationship between Fc epsilon R and CD23. This interesting observation warrants additional clarification as to the role of CD23 and Fc epsilon R in B cell differentiation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::0a36573dd6f4b6b3d934c2476354e5ea https://pubmed.ncbi.nlm.nih.gov/2951441 Zobrazit plný text záznamu