[Effect of therapy with antibiotics on lipid metabolism and antioxidant reserve of patients with ischemic heart disease during Chlamydia pneumoniae infection]

Autor:	V A, Klochkov, P Ia, Dovgalevskiĭ, K S, Umetskiĭ, N E, Chalyk, O M, Ansimova, N A, Zigangirova, I, Petiaev
Rok vydání:	2005
Předmět:	Adult Male Time Factors Myocardial Ischemia Azithromycin Chlamydophila pneumoniae Middle Aged Lipid Metabolism Antibodies Bacterial Antioxidants Anti-Bacterial Agents Data Interpretation Statistical Doxycycline Pneumonia Bacterial Humans Female Lipid Peroxidation Chlamydophila Infections Aged
Zdroj:	Kardiologiia. 45(12)
ISSN:	0022-9040
Popis:	Effect of therapy with azithromycin and doxycycline on lipid metabolism, processes of lipid peroxidation and state of antioxidant defense was studied in patients with ischemic heart disease with elevated titer of antibodies to Chlamydia Pneumonia. Therapy with azithromycin (500 mg/day for 2 months) was associated with lowering of antibody titer, moderate improvement of lipid spectrum, marked decrease of activity of lipid peroxidation and augmentation of blood plasma antioxidant reserve. There were no such changes in a group of doxycycline treated patients. This difference can be attributed to more pronounced antimicrobial activity of azithromycin against Chlamydophila Pneumonia and its intrinsic antioxidant properties.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::0997cc5cbe47d293611b9b10db806ddf https://pubmed.ncbi.nlm.nih.gov/16353050 Zobrazit plný text záznamu