Effect of subminimal inhibitory concentrations of penicillin on hyaluronidase production by group A streptococci

Autor: L C, Benchetrit, C C, Avelino, C M, de Oliveira
Rok vydání: 1981
Předmět:
Zdroj: Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectious.... 251(2)
ISSN: 0174-3031
Popis: A sensitive dye-binding assay was employed to study the extracellular hyaluronidase produced by three penicillin-sensitive strains of group A streptococci belonging to M types 4, 24 and 28. Enzyme was produced by all strains at appreciable levels. Subminimal inhibitory concentrations of penicillin in growing cultures increased enzyme production by M types 4 and 24 strains. Growth of the M type 28 R strain with added antibiotic was accompanied by a reduced production of hyaluronidase.
Databáze: OpenAIRE