Retrospective study on the etiological spectrum and antibiotic resistance in infections associated with osteosynthesis materials
| Autor: | D, Tucaliuc, O, Alexa, Cristina Gabriela, Tuchiluş, Ramona Gabriela, Ursu, Elena Simona, Tucaliuc, Luminiţa Smaranda, Iancu |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Staphylococcus aureus Prosthesis-Related Infections Acinetobacter Romania Drug Resistance Microbial Microbial Sensitivity Tests Staphylococcal Infections Internal Fixators Anti-Bacterial Agents Fracture Fixation Internal Fractures Bone Traumatology Fracture Fixation Risk Factors Drug Resistance Multiple Bacterial Pseudomonas aeruginosa Prevalence Humans Female Enterococcus Retrospective Studies |
| Zdroj: | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. 118(1) |
| ISSN: | 0048-7848 |
| Popis: | To determine the prevalence of infections according to their etiologic spectrum and antibiotic sensitivity in patients with or without implants and endoprostheses.This retrospective study was conducted based on a customized study protocol on 773 cases admitted to the Clinic of Orthopedics - Traumatology of the Iaşi "Sf. Spiridon" Emergency Hospital in the interval January 1, 2003 - December 31, 2011 for postoperative infectious complication.S. aureus was more frequently found in the patients without implant (58.2%) and in those with subcutaneous implant (45.5%); the lowest frequency was noticed in the patients with endoprosthesis (27.1%), the frequency distributions showing marked statistically significant differences (p = 0.001). P. aeruginosa was more frequently detected in the patient group with endoprosthesis (30.2%), while in the other groups it was found in approximately 7% (p = 0.001). The presence of Acinetobacter spp. was significantly higher in patients with deep implant (12.9%), with the lowest frequency noticed in the patients without implant (4.5%) (p = 0.029). Of the total isolated and identified types, 59.6% were non-multidrug-resistant (non-MDR), the remaining 40.4% being MDR types.S. aureus was the most frequent etiological agent in patients with or without cutaneous implant (45.5 and 58.2%, respectively), and P. aeruginosa (30.2%) in the endoprosthesized patients. Implementation of a preoperative screening protocol for the identification of healthy S. aureus carriers (Methicillin-sensitive S. aureus - MSSA/Methicillin-resistant S. aureus - MRSA) and subsequent decolonization would be an efficient way of reducing the incidence of infections caused by this bacterium. |
| Databáze: | OpenAIRE |
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