| Autor: |
Yuan-Yuan, Long, Cheng-Shuang, Huang, Pei, Huang, Hong-Bo, Xu, Chuang, Xie, Yan, Chen |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Zhongguo shi yan xue ye xue za zhi. 29(1) |
| ISSN: |
1009-2137 |
| Popis: |
To investigate the difference in the therapeutic effect of plasma exchange and continuous renal replacement therapy (PE+CRRT) combined with chemotherapy in the treatment of children with severe Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH) and non-EBV-HLH.The clinical data of 21 cases of all children with severe HLH treated by PE+CRRT combined with chemotherapy from January 2017 to January 2020 were collected and retrospectively analyzed. According to the presence of EBV infection, the children were divided into EBVAmong the 21 children, 14 were divided into the EBVPE+CRRT combined with chemotherapy can reduce serum ferritin quickly, then improve organ function, and increase the overall survival rate of severe HLH, and it is a good effect on children with severe EBV-HLH and non-EBV-HLH.PE+CRRT联合化学免疫疗法治疗儿童重型EBV-HLH和非EBV-HLH的疗效观察.探讨血浆置换与连续性肾脏替代疗法(PE+CRRT)联合化学免疫疗法在儿童重型EB病毒相关噬血细胞综合征（EBV-HLH）和非EBV-HLH中疗效的差异.收集并回顾性分析2017年1月至2020年1月所有接受PE+CRRT联合化学免疫疗法的21例重型HLH患儿的临床资料，根据是否存在EBV感染，将患儿分为EBV21例患儿中，EBVPE+CRRT联合化学免疫疗法可快速降低血清铁蛋白、改善器官功能，提高重型HLH总生存率，且对儿童重型EBV-HLH和非EBV-HLH均有较好的疗效，是治疗HLH的有效方法. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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