Immunohistochemical aid at risk stratification of melanocytic neoplasms
| Autor: | Pascale, Quatresooz, Jorge E, Arrese, Claudine, Pierard-Franchimont, Gerald E, Pierard |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Skin Neoplasms
Monophenol Monooxygenase S100 Proteins Antibodies Monoclonal Proteins NM23 Nucleoside Diphosphate Kinases Prognosis Immunohistochemistry Neoplasm Proteins Ki-67 Antigen MART-1 Antigen Antigens Neoplasm Nucleoside-Diphosphate Kinase Biomarkers Tumor Humans Plant Lectins Factor XIIIa Melanoma Melanoma-Specific Antigens Glycoproteins Retrospective Studies |
| Zdroj: | International journal of oncology. 24(1) |
| ISSN: | 1019-6439 |
| Popis: | There is increasing awareness of the population about the risk of cutaneous melanoma. In recent years, some improvement was gained in the early recognition of clinical warning signs using dermoscopy. As a result, the number of puzzling cases exhibiting limited classical clues for malignancy are submitted to the dermatopathologist. Thus, the risk of microscopic uncertainty or misdiagnosis may be increasing. The aim of the study was to assess retrospectively the contribution of immunohistochemistry in establishing the histological diagnosis of 520 melanocytic neoplasms. According to the disease evolution and the histological presentation, 6 profiles of phenotypical expressions were distinguished. |
| Databáze: | OpenAIRE |
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