| Autor: |
Abigail R, Hanby, Nikolaj S, Troelsen, Thomas J, Osberger, Sarah L, Kidd, Kim T, Mortensen, David R, Spring |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Chemical communications (Cambridge, England). 56(15) |
| ISSN: |
1364-548X |
| Popis: |
Herein, we describe the natural product inspired synthesis of 38 complex small molecules based upon 20 unique frameworks suitable for fragment-based screening. Utilising an efficient strategy, two key building block diastereomers were harnessed to generate novel, three-dimensional fragments which each possess numerous synthetically accessible fragment growth positions. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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