[Search for and study of biologically active substances with psychotropic activity among the N-nicotinoyl derivatives of glutamic and gamma-aminobutyric acids]

Autor:	G I, Kuz'menko, L E, Gotsuliak, A I, Gaĭdenko, A D, Kazanov, M F, Niiaka
Rok vydání:	1988
Předmět:	Mice Psychotropic Drugs Structure-Activity Relationship Cell Membrane Permeability Dose-Response Relationship Drug Glutamates Nicotinic Acids Animals Glutamic Acid Motor Activity gamma-Aminobutyric Acid
Zdroj:	Farmakologiia i toksikologiia. 51(1)
ISSN:	0014-8318
Popis:	Four new derivatives of glutamic and gamma-aminobutyric acids influencing the central nervous system were produced. By the character of their action they refer to the substances of the sedating tranquilizing type without the myorelaxant component. The drug activity degree depends on its ability to penetrate through cell membranes that is in turn determined by the structure of the compound.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::081c6fb35173238ac1807ce816a418c0 https://pubmed.ncbi.nlm.nih.gov/2896131 Zobrazit plný text záznamu