| Autor: |
Lourdes, Vicent, Miguel Angel, Goenaga, Patricia, Muñoz, Mercedes, Marín-Arriaza, Maricela, Valerio, M Carmen, Fariñas, Manuel, Cobo-Belaustegui, Arístides, de Alarcón, M Ángeles, Rodríguez-Esteban, J M, Miró, Ane Josune, Goikoetxea-Agirre, Daniel, de Castro Campos, Elisa, García-Vázquez, Manuel, Martínez-Sellés |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Pediatric research. 92(5) |
| ISSN: |
1530-0447 |
| Popis: |
Our aim was to compare pediatric infective endocarditis (IE) with the clinical profile and outcomes of IE in adults.Prospective multicenter registry in 31 Spanish hospitals including all patients with a diagnosis of IE from 2008 to 2020.A total of 5590 patients were included, 49 were18 years (0.1%). Congenital heart disease (CHD) was present in 31 children and adolescents (63.2%). Right-sided location was more common in children/adolescents than in adults (46.9% vs. 6.3%, P 0.001). Pediatric pulmonary IE was more frequent in patients with CHD (48.4%) than in those without (5.6%), P = 0.004. Staphylococcus aureus etiology tended to be more common in pediatric patients (32.7%) than in adults (22.3%), P = 0.082. Heart failure was less common in pediatric patients than in adults, due to the lower rate of heart failure in children/adolescents with CHD (9.6%) with respect to those without CHD (44.4%), P = 0.005. Inhospital mortality was high in both children, and adolescents and adults (16.3% vs. 25.9%; P = 0.126).Most IE cases in children and adolescents are seen in patients with CHD that have a more common right-sided location and a lower prevalence of heart failure than patients without CHD. IE in children and adolescents without CHD has a more similar profile to IE in adults.Infective endocarditis (IE) in children and adolescents is often seen in patients with congenital heart disease (CHD). Right-sided location is the most common in patients with CHD and heart failure is less common as a complication compared with patients without CHD. Infective endocarditis (IE) in children/adolescents without CHD has a more similar profile to IE in adults. In children/adolescents without CHD, locations were similar to adults, including a predominance of left-sided IE. Acute heart failure was the most frequent complication, seen mainly in adults, and in children/adolescents without CHD. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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