Hydrogen sulfide prevents the vascular dysfunction induced by severe traumatic brain injury in rats by reducing reactive oxygen species and modulating eNOS and H

Autor: Félix I, López-Preza, Saúl, Huerta de la Cruz, Cindy, Santiago-Castañeda, Diana L, Silva-Velasco, Jesus H, Beltran-Ornelas, Jorge, Tapia-Martínez, Araceli, Sánchez-López, Luisa, Rocha, David, Centurión
Rok vydání: 2022
Zdroj: Life sciences. 312
ISSN: 1879-0631
Popis: To assess the effects of subchronic administration with NaHS, an exogenous HAnimals underweministration does not prevent the body weight loss but slightly imnt a lateral fluid percussion injury, and the hemodynamic variables were measured in vivo by plethysmograph method. The vascular function in vitro, the ROS levels by the DCFH-DA method and the expression of HTBI animals showed: 1) an increase in hemodynamic variables and ROS levels in aortas; 2) vascular dysfunction; 3) sensorimotor dysfunction; and 4) a decrease in body weight, the expression of HTaken together, these results demonstrate that H
Databáze: OpenAIRE
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