| Autor: |
Convit, J., Browne, S. G., Languillon, J., Pettit, J. H. S., Ramanujam, K., Sagher, F., Sheskin, J., Lima, L. de Souza, Tarabini, G., Tolentino, J. G., Waters, M. F. R., Bechelli, L. M., Domínguez, V. Marténez |
| Jazyk: |
angličtina |
| Rok vydání: |
1970 |
| Předmět: |
|
| Popis: |
The latest developments and ideas in the therapy of leprosy are discussed, the need for long-term studies being stressed. The therapeutic efficacy and effective dosages of some sulfones (especially diaphenylsulfone), thiambutosine and long-acting sulfonamides such as sulfamethoxine and sulfalene, are considered. The possibilities for two newer drugs, 4,4'-diacetyldiaminodiphenylsulfone and clofazimine (B-663), both still in the early stages of evaluation, are also described and the potential value of thalidomide in treatment of the lepra reaction is discussed. The authors make a number of recommendations for controlled trials and lines of investigation and, in particular, favour a biochemical approach to the correction of defective host defences. Diaphenylsulfone is still considered the drug of choice for use in the therapy of leprosy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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