Evaluation of Betulinic Acid Derivatives as PET Tracers for Hypoxia-Induced Carbonic Anhydrase IX (CA IX) Expression

Autor: V, Haupt, D, Gündel, E, Prell, M, Kahnt, S, Sommerwerk, A, Riemann, R, Paschke, R, Csuk, A, Odparlik, O, Thews
Rok vydání: 2022
Předmět:
Zdroj: Advances in experimental medicine and biology. 1395
ISSN: 0065-2598
Popis: Non-invasive visualisation of the expression of hypoxia-related proteins, such as carbonic anhydrase IX (CA IX), by positron emission tomography (PET) could provide important information on the oxygenation status of tumours. Since betulinic acid derivatives bind specifically to CA IX the aim of the study was the development betulinic acid-based
Databáze: OpenAIRE