| Autor: |
Qing-shan, Shen, Yong-sheng, Liu, Rui, Zhu, Du-guan, Fu, Yong-qian, Tang, Hong, Tao, Su-zhen, Li, Jian-wen, Ye |
| Rok vydání: |
2005 |
| Předmět: |
|
| Zdroj: |
Zhonghua xin xue guan bing za zhi. 33(4) |
| ISSN: |
0253-3758 |
| Popis: |
To investigate the effect of fluvastatin on blood levels of c-reactive protein (CRP), tumor necrosis factor alpha (TNFalpha) and cardiac troponin I (cTnI) in patients with unstable angina undergoing percutaneous coronary intervention (PCI).Sixty patients who underwent PCI from July 2002 to April 2004 in our hospital were randomized into two groups: control group; fluvastatin group (40 mg/d). Serum levels of CRP, TNFalpha and cTnI were measured before and after two weeks treatment (in the early morning of the procedure) and at 24 hours after the procedure.The serum levels of CRP, TNFalpha and cTnI in fluvastatin group were distinctly lower than those in control group before (P0.01) and after the procedure (P0.01), respectively.The result suggested that PCI could lead to a detectable increase in serum levels of CRP, TNFalpha and cTnI in patients with coronary heart disease; Fluvastatin could significantly decrease the serum levels of CRP, TNFalpha and cTnI in patients with coronary heart disease; Fluvastatin could also decrease the serum levels of CRP, TNFalpha and cTnI in patients with PCI. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
