| Autor: |
B, Orcel, B, Delclaux, M, Baud, J P, Derenne |
| Jazyk: |
francouzština |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Revue des maladies respiratoires. 10(1) |
| ISSN: |
0761-8425 |
| Popis: |
Three hundred fifty six patients aged 65 years or more (mean age 81.8 years) who were suffering from chronic bronchitis were included in a double-blind trial against placebo to assess the preventative effect of OM-85 BV against acute exacerbations of chronic bronchitis. OM-85 BV is an immunostimulant composed of lyophilised factions of 8 bacteria which are most frequently encountered during the course of respiratory tract infections. 291 patients completed the study. In the group treated by OM-85 BV, a significant increase in the number of patients with no episode of acute bronchitis was noted (96 versus 71, p = 0.006). There was a 38.8% reduction in the absolute numbers of episodes of acute bronchitis and a 33% reduction in the number of prescriptions for antibiotics, however there was no difference in the number of pneumonias and bronchopneumonias. These results show the protective effect of OM-85 BV against bronchial superinfections in a large population of elderly patients suffering from chronic bronchitis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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